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Orlica (Orlistat)

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Orlica is used together with a reduced-calorie diet to help you lose weight and to help keep the lost weight from returning. It is also used in overweight people who may also have diabetes, high blood pressure, high cholesterol, or heart disease.

Other names for this medication:
Cobese, Lipophage, Nipocut, Obelit, Obfree, Obilix, Obitrol, Olisat, Orlica, Orlimac, Orlistat, Orlitroy, Reeshape, Slimfast, Troyslim, Vyfat, Zerofat

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Also known as: Orlistat


Orlica capsules are manufactured by Roche. The active component of Orlica is Orlistat (also known as tetrahydrolipstatin) – a gastrointestinal lipase inhibitor. Orlica is recommended to control obesity in patients with the BMI greater or equal to 30 kg/m² (or with BMI greater or equal to 28 kg/m² with associated risk factors). Taking Orlica helps to lose weight, keeps from gaining it back and thus reduces many health risks that come with obesity, including heart disease, diabetes, high blood pressure etc.


Orlica is taken orally 3 times a day during the main meal or up to 1 hour after the meal. The diet of the patient should include three main meals, containing the daily dose of fat, carbohydrate, and protein. The daily intake of fat should be no more than 30% of your total daily caloric intake (e.g., eating 1200 calories per day, no more than 360 of those calories should be in the form of fat). The dose of Orlica should be omitted if a meal is missed or does not contain fat. Treatment with Orlica should not continue for more than 6 months and should be stopped after 12 weeks if patient has been unable to lose at least 5 % of the body weight. If you lose enough weight for your BMI to fall below 28 kg/m², Orlica can no longer be supplied.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) and away from excess moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Avoid eating high-fat meals or you could have unpleasant side effects on your stomach or intestines.

If you also take cyclosporine, do not take it within 3 hours before or 3 hours after you take Orlica.

If you also take levothyroxine (such as Synthroid), do not take it within 4 hours before or 4 hours after you take Orlica.

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